Research

Finite Element Modeling of the Ear
  • Excellent tool for simulating sound and blast wave transmission
  • Constructed based on accurate anatomy of the ears
  • Coupling of the fluid and solid systems
  • Simulating 3-dimensional mechanical responses in frequency and time domains
  • Validated by experimental results obtained from biomechanical and physiological measurements

Ear Biomechanics
  • Static and dynamic properties of ear tissues are critical for hearing
  • Laser Doppler vibrometry measured the vibration of ear tissues at high frequencies
  • 3D Printing technology reconstructed the human ear following the experimentally measured mechanical properties

Blast Biomechanics
  • Investigating the mechanism of blast-induced auditory injuries
  • Characterize the nonlinear response of the ear under blast conditions
  • Provide data to validate the finite element models

Development of Hearing Protection Devices
  • Evaluating the protective function of hearing protection devices under normal and blast conditions
  • Multiple platforms used for function assessment: Blast tests, FE simulation, and acoustic testing fixture
  • Improve the protective function by adjusting the geometry of the earplugs
  • Development of new generation earplugs made of nano aerogel material

Therapeutic Solutions to Blast-induced Auditory Injuries
  • Liraglutide is a glucagon-like peptide-1 receptor agonist for diabetes treatment
  • Preliminary studies on chinchillas indicated the liraglutide treatment mitigated the blast-induced hearing loss
  • The mechanisms of the liraglutide treatment are under investigation

Implantable Hearing Devices
  • The totally implantable hearing system (TIHS) was initiated by Dr. Rong Z. Gan after joining OU in 1999
  • The components of TIHS such as the implantable coil and implant magnet are designed using our 3-D FE computer model of the human ear and tested in human cadaver ears.
  • SOUNDTEC Direct System is an FDA-approved middle ear partially implantable electromagnetic device
  • Dr. Rong Gan was the leading researcher to accomplish the design and in vitro testing of the SOUNDTEC Direct System